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hueco


Nov 2, 2002, 12:18 AM
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Glucosamine
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I am curious about people's experiences with Glucosamine supplements. Positive, negative, no results? It's expensive but I decided to give it a try because my fingers are always achy.

Any other supplements that people recommend?

Advil daily or just after climbing?

If this has been discussed previously, please refer me to a previous post.


cloudbreak


Nov 2, 2002, 12:40 AM
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I take a glucosimine/chondroitin(sp?) supplement daily. I hear ya on the cost, it's real pricey. If you have a Costco/Sam's Club nearby, they carry a generic version of it, with the exact same ingredients, but WAY cheaper.....250 tablets/$19.99. As far as results, I can't say personally, but I know people(parents) that feel they have greatly benefitted from it.

Marc


kiwidave


Nov 2, 2002, 12:40 AM
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yeah i have used glucosamine for tweeky pullies which i pulled while climbing. I saw a friend who owns a health food shop and recommended that i try it. It was a micro genetics one. What i found was good. It dosent fix your pulled pullies over night but it fixs them a lot quicker than if you werent taking it. It was also recommended to keep taking it afterwards becuase it provides an ensyme which aids faster recovery over tendons and helps with atheritis. continued use helps prevent injury again and i think work them a lot harder without feeling as sore the next day. In New Zealand, rugby players take it to help prevent and cure injury to these areas like ankles an arckillies. i have stopped taking it but have found that my fingers are as strong as ever and no probs with the old injury. Also if your fingers hurt try resting and stretching them just by gently bending them backwards. after a short rest take it easy to let your fingers get used to the load again. This is based on my own experiance and what i have talked to people about. Hopes this helps and let me now what you think

Dave


astone


Nov 2, 2002, 12:52 AM
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I had awesome results with glucosamine after ankle surgery. It helped my achilles tendon heal up very nicely.


marcel


Nov 2, 2002, 12:59 AM
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It sure works on bad knees!


cyberhobo


Nov 2, 2002, 1:05 AM
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I have read an evaluation of Glucosamine studies that indicated that it _may_ be effective for enhancing regeneration of cartilege in cases of arthritis, and also may slow cartilege degradation in athletes. I concluded that it might be worth taking to prevent wear on joints.

Studies that tested Glucosamine Sulfate and Glucosamine Hydrochloride generally reported better results than other forms.

This is from memory - I can look up my source given a few days if you must know it...


boz84


Nov 2, 2002, 3:11 AM
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We give my older dog glucosamine/chondritin that is made for dogs. It has visibly improved the pain he sometiems feels when walking.

It used to take him 10-15 seconds to sit down or stand up, but since taking the supplements, taht has drmaticaly decreased.


gunked


Nov 2, 2002, 3:36 AM
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There is an older post about Glucosamine. Regardless, I work for a company that's only product is a Glucosamine drink called Joint Juice.

The current findings are as follows:
-Glucosamine works for about 75% to %80 of people who try it.
-The recommended daily doseage is 1500 mg.
-It needs to be taken every day to be effective.

Oh who am I kidding, this could take a while. To whoever's interested, please reply with a request for specific information. If I don't have it at hand, I can probably get a hold of it pretty easily.

Long story short, the stuff works pretty well for most people and enough to justify the expense.
Jason


jansuw


Nov 2, 2002, 4:44 AM
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Sounds really good, but are there any negative side effects? Short or long term... Seems like this hasn't even been considered


gunked


Nov 2, 2002, 7:37 AM
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This has been considered.
Testing on Glucosamine started around 1980. There are no known negative side-effects to Glucosamine in either sulfate or hydrochloride (liquid) form.

The other day I noticed that one company that makes a Glucosamine product actually tells people with shellfish allergies to not take the product.

Glucosamine is derived from the shells of shellfish. The allergies, however, are a result of the protein found in the meat, not the shell. This company clearly didn't do their homework.

Long story short, Glucosamine is safe.

Jason


thomasribiere


Nov 2, 2002, 1:15 PM
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I used them in the 80's for knee problems with no result as I can remember.

But now as a vet, I prescribe them for dogs with degenerative joint disease. It works pretty well, though some dogs can get diarrhea...

Their aim is to modify the anatomical structure of the cartilage ; they are also known as symptomatical molecules with anti DJD with slow action (over 4 weeks).

Glucosamine is a small molecule derievd from glucose ; it's a monomere for glucosaminoglycanes (keratane, hyaluronate...)

Chondroitine, (extracted from cow trachea, squales, mussels shells...), is a polymere of high molecular weight which is partially absorbed in the bowel. The absorbed part has a high affinity for bone epiphysis et synovia, ie the joints.

However, the action lasts for weeks (4to8 weeks), much higher than placebos.
The radiographic studies show a stabilisation of the lesions (not an improvement).

Moreover, the use of glucosamine and/or chondroitine allows a reduction of the use of the anti-inflammatory drugs, which is good.

And as a vet, I can see the results on dogs which are goods. But yes, it's expensive, and you have to make 2 or 3 cures of 1 month each avery year.

I don't know if it works on tendon, it's not the purpose of this drugs!

HOPE THIS HELPED YOU!


micahmcguire


Nov 2, 2002, 11:12 PM
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a godsend and a breakthrough in pharaceutical therapy. Take it even if you don't think you have degenerating tendons and joints. Its good for you any way you slice it.


bighigaz


Nov 3, 2002, 12:58 AM
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Okay, I've got aches and pains, and I'm definately up for tryin Glucosimine... but It's going to run about $30 an month to get a descent amount. I recently read that GRAPE SEED Extract is super potent, and has the same general effects, with some added advantages... besides the fact that it is a natural extract... not so artificial seems like a better idea... just a thought.


jgill


Nov 3, 2002, 1:59 AM
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For a reasonable product, try Shiff "Glucosamine 1000" sold by Walmart. I think it costs about $16 for a month's supply. Two huge tablets a day. It seems to have helped my knees.


katydid


Nov 3, 2002, 11:30 AM
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I tried an MSM/glucosamine combo, but it upset my stomach so badly I couldn't continue it long enough to get results. Before I go spend a zillion dollars on glucosamine without MSM, does anyone know which causes the tummy-ache?

I'm 31, but my left knee's about 70. It could use the help.

Kate


estherator


Nov 5, 2002, 6:23 PM
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I have so many old joint injuries at 29 that it's ridiculous. (That's what happens when you're too stubborn to quit when your biody tells you to) However, when I'm taking my supplements, I've little to no symptoms, when I stop for a week, they start acting up again. Glucosamine Sulfate, and Chondroitin for the cartilage and synovial fluids; MSM for soft tissue. GNC makes it in one supplement and so does worldimagenaturals.com. They are both quality products.

If you are allergic to shellfish or sulfur-do not take these supplements!


jhwnewengland


Nov 5, 2002, 6:30 PM
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As gunked said earlier, the shellfish allergy is false. Glucosamine is made from their shells, not their meat (which is what one can be allergic to).

I take Glucosamine/Chondroitin/MSM and it's definitely helped with my tendonitis and several knee injuries. Less pain. I've had no negative side effects.

Jan


tradguy


Nov 5, 2002, 6:39 PM
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Maybe I missed it, but what is MSM (ie what does it stand for)? And what are its benefits? Someone said something about soft tissue - presumably tendons and ligaments?

I had ACL surgery a year ago, and while somedays my knee seems completely fine, others it is sore and painful. Really sucks. I think the ACL is fine, but there was some cartiledge damage also that I think didn't really heal up too well. I've been thinking about trying some of this stuff, but not sure. I like the idea of getting it cheap, but is the Walmart stuff as good as the stuff from GNC (typically expensive, I think). How much are you guys paying at GNC for a month's supply?


lynne


Nov 5, 2002, 6:41 PM
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Do not take glucosamine if you are diabetic. While it has helped my old knees and back and shoulder tremendously, my doctor is convinced it has contributed to my insulin resistance. Apparently there is solid research supporting this theory.


katydid


Nov 6, 2002, 12:08 AM
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MSM's a DMSO derivative.

Kate


jhwnewengland


Nov 8, 2002, 3:44 AM
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MSM stands for Methylsulfonylmethane (as if that meant anything to anyone). The stuff at Walmart should be just as good as the GNC stuff.. They're just minerals, really.

All three are for joints and tissues, but I'd say Glucosamine/Chondroitin is the more serious combo for ligaments and tendons. They all contain sulfur, which is a building block of joints and tissues (MSM is actually a source of sulfur). Can't hrt to go with all three if you can spare the dough.


bighigaz


Nov 29, 2002, 2:00 AM
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Okay, I started taking glucosimine about two weeks ago... I have 45 days worth, and I am curious to see how much better I feel in a month... It's supposed to take actual effect after 2 or three months... I'll keep you all informed on my progress... (and I promise I'll let you know if I start getting boobs. )

[ This Message was edited by: bighigaz on 2003-01-06 06:34 ]


curt


Nov 29, 2002, 2:24 AM
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I believe that most of the hard evidence for glucosamine effectivness relates to cartilidge, rather than tendons. However, my fingers do seem less sore after bouldering since I been taking glucosamine--so maybe it does some good. As someone posted above, the recommended dose is 1500 mg/day.

Curt


wallrat


Nov 29, 2002, 3:23 AM
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   I've had really good luck with four things for joints. It looks like the Glucosamine/Chondroitin is about the single best, but also look at MSM, and simple Gelatine, as in Knox & Jello (didn't know it was a health suplement did you?) which you can find in bulk in any good health food place. Without them, I'm toast. Luck to you, Gene.


ksfrogman


Dec 3, 2002, 5:16 AM
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Nice thread. Interesting comments. I actually bought some for my 69-year-old mom for her arthritic knees and she says it has really helped her. As a climber, maybe I shouldn't wait till I'm that age.


jt512


Dec 3, 2002, 7:13 AM
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Curt's got it right. I'm a nutrition researhcer and I've never been able to find any hard evidence in the scientific literature that glucsoamine is effective for tendon injuries. In contrast, I'm convinced that it is an effective treatment for cartilage damage, especially in the knees.

Glucosamine is a mild anti-inflammatory, and hence might be beneficial in tendon injury; however, there are probably better anti-inflammatories available over-the-counter (eg, ibuprofen) or by prescription (eg, Vioxx).

-Jay


bighigaz


Jan 6, 2003, 1:38 PM
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Okay, I am now an official Glucosimine/MSM supporter. I started taking a tablet (From Wal Mart) twice a day that is 500mg MSM/500mg Glucosimine. After about 6 weeks I noticed a BIG difference. I thought it might be in my head, so I stopped taking it and about a week later my knees and ankles were back to there old selves again-- hurting most of the time. Not only did it help with my joints, but I also took vitamin C right along with it, and I have honestly not felt this good in a long time! This stuff works, I'll vouch for it.


crankenstein


Jan 6, 2003, 1:53 PM
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Glocosamine/Chondroitin Sulfate is the greatest stuff for cartiledge damage. I can hardly walk due to an arthritic ankle when I don't take the stuff, but when I do I am fully mobile. I used to take up to 8 Advils a day, but now I feel that I get the same results on 1000mg of Glocosamine daily without the side effects. I have been told by 3 orthopaedic doctors that the Glocosamine is much less harmful to my body and the fact that it works so well for me makes it a wonder drug in my opinion.


thegib


Jan 6, 2003, 2:23 PM
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On possible side effects:

I used glucosamine when I was just beginning to climb harder stuff. The new crimpy holds were taxing my first finger joints. It seems to have worked (my joints stopped hurting) but I can't say for sure whether this was due to the supplement or just my body naturally adapting.

However, I also do martial arts, and I noticed that I was straining my muscles more frequently while on glucosamine. My legs and particularly my hamstrings always felt a little more tweaky and brittle.

I'm curious, has anybody else experienced this?


bighigaz


Jan 6, 2003, 2:42 PM
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Gib, I'm not an autority on nutrition by anymeans, but I haven't noticed any problems with side effects since I've been using Gluc./MSM. But in support of the 'wonder drug,' maybe you're just lacking the right nutrition for your mucsles? I wrestled a year in college, and you'd be amazed what proteins from beef and chicken will do to help your muscle developement and healing... My coach was always concerned with whether or not we were "getting enough red meat." Most of us poor college kids weren't, so a juicy steak, or bucket of mmm-mmm chicken seemed to work wonders. ...and if your a veggy, there are protein supplements that can give you the same nutrition. (I prefer the meat!!!) I'd go to a nutritionist, though, and make sure you get the best advice... it's not worth an injury that would stop your climbing!
James.


rprp


Jan 7, 2003, 1:30 AM
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I took glucosamine for a while. It either helped or I just got better anyway. After taking it for a few months I dropped down to a single 500mg pill a day on the idea that it might help prevent future problems.

I didn't take it at all for most of the last year, and was thinking of restarting. Does anybody know if there has been research on the usefulness of lower dose "preventative" programs? Or is less than 1000mg a day a waste?


bighigaz


Mar 17, 2003, 2:23 PM
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Okay, I started this post a few months ago and thought I'd give my take on the miracle drug. It's FANTASTIC! I take 500mg's 2 times daily, and it has an MSM supplement as well. I feel like my joints are back to normal, and I am now a full supporter of Glucosimine. I tried a couple of different brands, and one with chondroitin instead of MSM... MSM seems to work a little better, and I guess is supposed to help facilitate the absorption of the Glucosimine. Anyway, I like it and I definately recommended. Now I only hope they'll sponsor me!! :roll:


mustclimb69


Mar 17, 2003, 3:10 PM
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glucosamine, I have used it for my knees and it works but is pricy. My chriopractor/natural path informed me that by eating cartlidge my body obtains all the nutrients it needs to help speed up recovery and prevent joint injuries. Next time you are eating wings or ribs eat the cartlidge. Doens't taste like anything and works. Plus it is a reason to eat more wings and ribs!
Good luck


redpoint73


Mar 17, 2003, 3:27 PM
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I have heard that the notion that ingesting shark or other animal cartilage helps your joints is a myth. But I don't personally know of any scientific studies that support or refute this notion. Anyone have any specific knowledge? I think there may have been a reference to shark cartilage in Climbing magazine a while back (refuting its effectiveness), but I'm not sure.

I did a bit of reserch on Glucosamine a while back, and if I remember correctly, there is at least one study that suggests that it is helpful for healing or maintaining joints. But there is not a heck of a lot of reserch that has been performed yet (like many diet supplements).


bighigaz


Apr 18, 2003, 11:22 PM
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Okay, I've been taking glucosimine for several months now, and I just want to say frankly that it works. I have noticed an enormous difference, and I feel like I'm able to work and play much more than when my joints were giving me problems. I highly recommend it.

James


mainline


Apr 22, 2003, 1:55 AM
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I found this article on the web.

GLUCOSAMINE SAFE? EFFECTIVE?

Gabe Mirkin, M.D.

A study in last week's British medical Journal, Lancet, shows for the first time that glucosamine helps to retard the breakdown of cartilage. Up to now, studies showed only that glucosamine helps to relieve pain. People with arthritis received either 1500 mg of glucosamine or placebo. X rays of their knees showed that the placebo group lost more distance between the bones of their knees than the glucosamine group.

The ends of bones at the knee joint are covered with cartilage, so the greater the distance between the bones on X ray, the greater the amount of cartilage. There is a serious problem with the study. People with arthritis often cannot fully straighten their knees, so it is impossible to use distance between bones to determine how much cartilage is lost. For example, if a person bends his knees a little, he will have the bones closer together than when he holds his knees straight. That means that anything that blocks pain will allow person to straighten his knees and have a greater distance between the bones at the knee. You should get the same benefit from any pain medicine. Furthermore, the study was sponsored by Rotta Research Group, who could gain billions of dollars from sales promoted by this study.

An earlier editorial in Lancet, raises questions about the safety of glucosamine (2). Most research shows that glucosamine can help to relieve some of the pain associated with arthritis (3), but does not help to prevent cartilaginous damage and has not been shown to heal broken cartilage. Therefore, it is no more effective in treating arthritis than aspirin, but costs more than aspirin, but less than most brand name arthritis pain drugs that your doctor prescribes.

Glucosamine helps form aggrecan, the part of cartilage that allows cartilage to swell and shrink, acting like a shock absorber to help protect your knees from the trauma of running and walking. Adding glucosamine to cartilaginous cells in a test tube causes them to increases production of aggrecan (4).

However, in light of this good news, you should know that glucosamine blocks the effects of insulin, causing blood sugar levels to rise and(5,6,7) increasing likelihood of suffering the side effects of diabetes in susceptible people.

1) Lancet January 27, 2001

2 )Mark Adams: editorial The Lancet July 31, 1999, 354(9176):353-354.

3) Muller-Fabbender et al. Glucosamine compared to ibuprofen in osteoarthritis of the knee. Osteoarthritis Cartilage. 1994;2:61-69.

4)Bassler et al. Stimulation of Proteoglycan production by glucosamine sulfate in chondrocytes isolated from human osteoarthritis articular cartilage in vitro. Osteoarthritis Cartilage. 1998;6:427-434.

5) Am J Physiol Cell Physiol 1996;270:C803-11.

6) Diabetes 1995;45:1003-10089.

7) Proc Assoc Am Phys 1998;110:422-432.


mr_phelps


Apr 22, 2003, 2:45 AM
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Re: Glucosamine Safe? Effective? [In reply to]
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So let me get this straight?
glucosamine -- joints, cartilage
MSM -- soft tissue, tendons?
was there a third supplement?


bighigaz


Apr 22, 2003, 2:49 AM
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Gluc, I love it. [In reply to]
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I've been using Gluc for several months, and I swear by it. I wouldn't be climbing right now if it weren't for the stuff... my right knee and right wrist and right elbow are all working normally now.

James.


falcon


Aug 11, 2003, 2:08 PM
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Glucosamine [In reply to]
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I just started taking Glucosamine w/o the Condroiton and have done some research on it as well. From what I can tell there is quite a difference between what is an unregulated product. Evidently the liquid form is more easily absorbed (duh), that some of the pill forms of glucosamine have very little actuall glucosamine in it or require that you take several pills a day.

Whats studies have been done do indicate that glucosamine helps in the regeneration of cartilege and that the people in the study were taking a minimum of 1500 mg a day. There is also some concern about what *else* may be in the product. Things like traces of mercury and lead so do your research. Finally, I have a friend who had a knee replaced and his doctor (an actual MD!) suggested that there is enough evidence that glucosamine and condroiton do help. I've decided to take glucosamine and am hoping it helps.

Go to Google, type in Glucosamine and start reading. Good luck.


jt512


Aug 11, 2003, 4:17 PM
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Re: Glucosamine [In reply to]
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In reply to:
Evidently the liquid form is more easily absorbed...

Can you substantiate that statement?

-Jay


alpnclmbr1


Aug 11, 2003, 6:21 PM
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Re: Glucosamine [In reply to]
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I found it kind of interesting that the president takes Glucosamine.
As far as I could tell I had noticeable results when taking it.
And in the days before glucosamine, I had good results with shark cartilage.


jt512


Aug 11, 2003, 6:26 PM
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Bs [In reply to]
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In reply to:
glucosamine, I have used it for my knees and it works but is pricy. My chriopractor/natural path informed me that by eating cartlidge my body obtains all the nutrients it needs to help speed up recovery and prevent joint injuries. Next time you are eating wings or ribs eat the cartlidge. Doens't taste like anything and works. Plus it is a reason to eat more wings and ribs!
Good luck

Yeah, consume more high-saturated-fat, high-cholesterol, high-calorie foods in order to obtain no benefit from a pseudo-scientific non-nutrient. Good advice!

-Jay


falcon


Aug 20, 2003, 11:45 PM
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Re: Glucosamine [In reply to]
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Go to this web sight and check it out. Or go to google and type in glucosamine. There is a lot a info on it.

http://www.arthritis-glucosamine.net/glucosamine/glucosamine-products.html

Falcon


josher


Aug 21, 2003, 12:03 AM
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msm [In reply to]
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you can probably get the stuff from pharmisudical supply places. We used to order MSM, Gloucosomine, and Condroitin in bulk for our horses. (Totally looked like kilos of coke when it came in) It was pretty cheap. (forget exactly how much.

http://www.pharmlineinc.com/ is where we got ours


mowz


Aug 21, 2003, 6:57 PM
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In response to the glucosamine post [In reply to]
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When you take supplements your body gets affected negatively. For example: If your body is producing chemical A at normal levels and you start to take supplements for chemical A, then your body will start produce less of chemical A because it now believes that it can receive it from an outside source. Once you are off the supplements, your body might take a long time to recover. I believe it's not good to take supplements.


curt


Aug 21, 2003, 7:08 PM
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Re: In response to the glucosamine post [In reply to]
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I can offer at least anecdotal evidence that glucosamine works. I have been taking it since March of this year, when I damaged the tendon/pulley in my LH middle finger. It is now fully recovered.

I have had this exact same injury before on other fingers and they all took much longer to heal than this one did--in one case up to 12 months. I am attributing this to the glucosamine/MSM/condroitin I have been using (1500mg/day) since the time of the injury. I could be wrong and this could be coincidence, but I did heal faster this time--and I am 10 years older than the last time I had this type of problem.

Curt

ps. I also believe that having the MSM with the glucosamine is important.


jt512


Aug 21, 2003, 8:54 PM
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Re: In response to the glucosamine post [In reply to]
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In reply to:
I can offer at least anecdotal evidence that glucosamine works. I have been taking it since March of this year, when I damaged the tendon/pulley in my LH middle finger. It is now fully recovered.

I have had this exact same injury before on other fingers and they all took much longer to heal than this one did--in one case up to 12 months. I am attributing this to the glucosamine/MSM/condroitin I have been using (1500mg/day) since the time of the injury. I could be wrong and this could be coincidence, but I did heal faster this time--and I am 10 years older than the last time I had this type of problem.

Curt

ps. I also believe that having the MSM with the glucosamine is important.

It is not clear to me why glucosamine would be of much benefit to a tendon injury. Although it is a mild anti-inflammatory, glucosamine is thought to act mainly by stimulating the production of joint cartilage. I've tried to find studies on the effects of glucosamine for tendon/ligament injuries and have never been able to find any.

-Jay


curt


Aug 21, 2003, 8:59 PM
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Re: In response to the glucosamine post [In reply to]
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In reply to:
In reply to:
I can offer at least anecdotal evidence that glucosamine works. I have been taking it since March of this year, when I damaged the tendon/pulley in my LH middle finger. It is now fully recovered.

I have had this exact same injury before on other fingers and they all took much longer to heal than this one did--in one case up to 12 months. I am attributing this to the glucosamine/MSM/condroitin I have been using (1500mg/day) since the time of the injury. I could be wrong and this could be coincidence, but I did heal faster this time--and I am 10 years older than the last time I had this type of problem.

Curt

ps. I also believe that having the MSM with the glucosamine is important.

It is not clear to me why glucosamine would be of much benefit to a tendon injury. Although it is a mild anti-inflammatory, glucosamine is thought to act mainly by stimulating the production of joint cartilage. I've tried to find studies on the effects of glucosamine for tendon/ligament injuries and have never been able to find any.

-Jay

Jay,

I agree and have read much the same thing. Still, something in there seems to have helped and I don't think it was just psychological. That's why perhaps I think the MSM may have played a role here. I understand MSM to be (more or less) an ingestible form of the active ingredient in DMSO. What do you think?

Curt


jt512


Aug 21, 2003, 9:21 PM
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Re: In response to the glucosamine post [In reply to]
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In reply to:
I agree and have read much the same thing. Still, something in there seems to have helped and I don't think it was just psychological. That's why perhaps I think the MSM may have played a role here. I understand MSM to be (more or less) an ingestible form of the active ingredient in DMSO. What do you think?

Curt

I've been unable to find any clinical research on MSM therapy for either tendon or ligament injury, and I don't know enough about the purported mechanism to comment.

-Jay


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