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adeptus
Jan 13, 2004, 10:06 PM
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Any experience with this stuff? It should be good for your ligaments and reduce the risk of injury.
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shervo
Jan 13, 2004, 10:16 PM
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It's realy good!! take it I think it's just mental, but at least it worked when i had tendonitis. If it's gonna make you feel better, go for it!
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gblauer
Moderator
Jan 13, 2004, 10:37 PM
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I take it and MSM (per my physician). It has helped reduce my joint pain significantly. (Knees and fingers). Stick with it, it takes 6-8 weeks to make a difference. I am experimenting with liquid glucosamine...it tastes vile, but seems to be more effective. Who knows...
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rockprodigy
Jan 14, 2004, 5:01 AM
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It seems to work for me, and the only drawback I'm aware of is the price (it's spendy).
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adeptus
Jan 14, 2004, 8:25 AM
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So it rebuilds joint tissue or that?
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kyhangdog
Jan 14, 2004, 11:28 AM
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I take the MSM +Glucosamine and it definitely lubes the joints. My knees used to crack and pop whenever I'd hike uphill, but not they're quiet and not painful. It's not expensive either. I go to GNC and it's about ten bucks for a month's supply. To be honest I've had the best results from the combination of MSM, Glucosamine, and Chondroitin.
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iltripp
Jan 14, 2004, 12:31 PM
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I started taking glucosamine about a month ago because I have developed a lot of joint pain in my hands. Recurring injuries, too many cracked knuckles, and what may be the start of arthritis (at age 21) have made my hands often feel painful and stiff, especially in the cold. One particular knuckle that I injured in a fit of anger was especially bad. While I haven't tried to crank on any rocks in extreme cold yet, I have done a little climbing and pain that was there two months ago doesn't occue any more...
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marcel
Jan 14, 2004, 1:59 PM
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I take the MSM + Glucosamine and fish oil tablets. It makes a big difference. When I'm climbing hard I double the amount taken.
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gblauer
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Jan 14, 2004, 2:01 PM
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In reply to: To be honest I've had the best results from the combination of MSM, Glucosamine, and Chondroitin. I completely agree.
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j_ung
Jan 14, 2004, 2:10 PM
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Oh hell yes. Glocosamine/chondroitin/MSM: my supplement coctail of choice.
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thomasribiere
Jan 14, 2004, 10:07 PM
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This topic was discussed at least once, starting the 11/02/2002. Here's what I wrote, ased on studies made on animals (as I'm a vet). I corrected the grammar mistakes BTW.
In reply to: I used them in the 80's for knee problems with no result as I can remember. But now as a vet, I prescribe them for dogs with degenerative joint disease. It works pretty well, though some dogs can get diarrhea... Their aim is to modify the anatomical structure of the cartilage ; they are also known as symptomatical molecules with anti DJD with slow action (over 4 weeks). Glucosamine is a small molecule derievd from glucose ; it's a monomere for glucosaminoglycanes (keratane, hyaluronate...) Chondroitine, (extracted from cow trachea, squales, mussels shells...), is a polymere of high molecular weight which is partially absorbed in the bowel. The absorbed part has a high affinity for bone epiphysis and synovia, ie the joints. However, the action lasts for weeks (4 to 8 weeks), much higher than placebos. The radiographic studies show a stabilisation of the lesions (not an improvement). Moreover, the use of glucosamine and/or chondroitine allows a reduction of the use of the anti-inflammatory drugs, which is good. And as a vet, I can see the results on dogs which are goods. But yes, it's expensive, and you have to make 2 or 3 cures of 1 month each every year. I don't know if it works on tendon, it's not the purpose of those drugs! HOPE THIS HELPED YOU! _________________ Resident Frenchman
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greyicewater
Jan 22, 2004, 3:21 PM
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i take msm with glucosamine... it does wonders. my joints are feeling awsome. i take 2 pills when i don't climb, and when i know i'm going to climb hard, i'll take 3.
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coylec
Jan 22, 2004, 3:40 PM
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I have/had tendonitis in my left wrist so bad I could barely type or climb. I ordered "Therapain Plus" from ReliefMart. ists Glucosamine and MSM. In a week, it has reduced swelling and pain so I can climb (gingerly) and type. its a spray on thing. It was 30 bucks, but since its working, i can't complain. coylec
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powrslave
Feb 6, 2004, 6:02 PM
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It will work regardless. Not sure what MSM is all about, but I used the GNC offering since it came with the Glucosamine. Big dose pills of Glucosamine/Chondroitin is what its all about.
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adeptus
Feb 16, 2004, 6:07 PM
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Glucosamine rules! I’ve been taking it for only 2 weeks now, but I already feel a difference. Usually my fingers get toasted from hang board sessions, but now they hardly feel sore. The effect is notable and there are no side effects. I can only recommend it to climbers, even if they don’t have present problems. Climbing will wear down you fingers and cause arthritis sooner or later, so why not start the prevention as soon as possible. Give it a try, you'll like it :P
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endrizzi
Feb 16, 2004, 6:48 PM
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In reply to: It's realy good!! take it I think it's just mental, but at least it worked when i had tendonitis. If it's gonna make you feel better, go for it! My old partner was PHD in health statistics. Studies lab results on experiments to verify they are statistically valid models. He said glucosamine and fish oil are they only two "herbal" type supplements that have statistically valid lab models. dreez
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craggy
Feb 16, 2004, 7:21 PM
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Use it. Love it. Forget the studies and tests. This stuff works. Glucosamine, Chondroitin, MSM. Take it, love it and thank GOD for the wo/man who invented these joint supplements.
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yttocs
Feb 16, 2004, 8:15 PM
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In reply to: good write up on glucosamine from someone not trying to sell it to you... http://www.quackwatch.org/01QuackeryRelatedTopics/DSH/glucosamine.html Note that this article is 2 years old and is therefore somewhat out of date. I'm sure there are better studies by now. Also, Glucosamine is designed to work on joints not ligaments like some people seem to think.
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chrisvalenzuela
Feb 16, 2004, 8:40 PM
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If the joint pain is caused by the wearing thin of the cartilage in your joints from overuse, you can regrow the stuff and glucosamine sulphate and MSM with cologen (gelatin) will provide the essential nutrients to promote the regrowth. The older you get the harder it is to regrow cartilage. 50% of the people who take glucosamine have good results. I have read that by taking it with MSM it is much more effective. It can take up to six months for you to get any noticeable results. Of couse it all depends on the amount of existing damage.
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missedyno
Feb 27, 2004, 1:50 PM
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okay, i just bought all this stuff... anyone know what it's best to take with? empty stomach, with food... night vs. day... i know some supplements can only be absorbed by the body if taken with a certain food or other supplement/vitamin. any ideas?
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jgrierson
Feb 27, 2004, 2:06 PM
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In reply to: This topic was discussed at least once, starting the 11/02/2002. Here's what I wrote, ased on studies made on animals (as I'm a vet). I corrected the grammar mistakes BTW. In reply to: I used them in the 80's for knee problems with no result as I can remember. But now as a vet, I prescribe them for dogs with degenerative joint disease. It works pretty well, though some dogs can get diarrhea... Their aim is to modify the anatomical structure of the cartilage ; they are also known as symptomatical molecules with anti DJD with slow action (over 4 weeks). Glucosamine is a small molecule derievd from glucose ; it's a monomere for glucosaminoglycanes (keratane, hyaluronate...) Chondroitine, (extracted from cow trachea, squales, mussels shells...), is a polymere of high molecular weight which is partially absorbed in the bowel. The absorbed part has a high affinity for bone epiphysis and synovia, ie the joints. However, the action lasts for weeks (4 to 8 weeks), much higher than placebos. The radiographic studies show a stabilisation of the lesions (not an improvement). Moreover, the use of glucosamine and/or chondroitine allows a reduction of the use of the anti-inflammatory drugs, which is good. And as a vet, I can see the results on dogs which are goods. But yes, it's expensive, and you have to make 2 or 3 cures of 1 month each every year. I don't know if it works on tendon, it's not the purpose of those drugs! HOPE THIS HELPED YOU! _________________ Resident Frenchman Interesting comments - I am also a veterinary surgeon and I have yet to see any convinving data published about animals (in English). If you have any reference that show that chondroitin sulphate and glucosamine are effective I would be interested. I work in a large referral hospital in the UK and myself and my collegues are not convinced. Much of the evidence for there effectiveness in animals is ancedotal and I am not aware of any well design studies that have been performed to test the drugs efficacy. As for people - dunno - not my field! Although from what I have reasearched the evidence for the usefulness in joint disease is good.
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treehugger
Feb 27, 2004, 2:29 PM
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In reply to: okay, i just bought all this stuff... anyone know what it's best to take with? empty stomach, with food... night vs. day... i know some supplements can only be absorbed by the body if taken with a certain food or other supplement/vitamin. any ideas? After meals, with water.
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endrizzi
Feb 27, 2004, 2:42 PM
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Friend of mine is PHD in Health Statistics/Epidemeology and says that Glucosimine and Fish Oil are the only two supplements that have valid statistics behind them that in fact help the body. I take them religiously. Hasn't grown any hair on my head though... dreez
In reply to: This topic was discussed at least once, starting the 11/02/2002. Here's what I wrote, ased on studies made on animals (as I'm a vet). I corrected the grammar mistakes BTW. In reply to: I used them in the 80's for knee problems with no result as I can remember. But now as a vet, I prescribe them for dogs with degenerative joint disease. It works pretty well, though some dogs can get diarrhea... Their aim is to modify the anatomical structure of the cartilage ; they are also known as symptomatical molecules with anti DJD with slow action (over 4 weeks). Glucosamine is a small molecule derievd from glucose ; it's a monomere for glucosaminoglycanes (keratane, hyaluronate...) Chondroitine, (extracted from cow trachea, squales, mussels shells...), is a polymere of high molecular weight which is partially absorbed in the bowel. The absorbed part has a high affinity for bone epiphysis and synovia, ie the joints. However, the action lasts for weeks (4 to 8 weeks), much higher than placebos. The radiographic studies show a stabilisation of the lesions (not an improvement). Moreover, the use of glucosamine and/or chondroitine allows a reduction of the use of the anti-inflammatory drugs, which is good. And as a vet, I can see the results on dogs which are goods. But yes, it's expensive, and you have to make 2 or 3 cures of 1 month each every year. I don't know if it works on tendon, it's not the purpose of those drugs! HOPE THIS HELPED YOU! _________________ Resident Frenchman
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cjain
Mar 9, 2004, 3:26 AM
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Searching for info on these supplements, from what I was able to gather there's some pretty decent support for glucosamine. Not so much for chondroitin but it what's out there it looks promising. Also, several medical doctors I know recommend them to their patients. MSM was a different story. Maybe I missed someting, but I wasn't able to find anything but empty hype on MSM--certainly nothing that comes close to justifying the claims being made.
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jt512
Mar 9, 2004, 3:31 AM
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In reply to: So it rebuilds joint tissue or that? Yes, and it is a mild anti-inflammatory. Whether it is helpful for tendon and ligament injuries is unknown.
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dlintz
Mar 9, 2004, 4:32 AM
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In reply to: Interesting comments - I am also a veterinary surgeon and I have yet to see any convinving data published about animals (in English). If you have any reference that show that chondroitin sulphate and glucosamine are effective I would be interested. I work in a large referral hospital in the UK and myself and my collegues are not convinced. Much of the evidence for there effectiveness in animals is ancedotal and I am not aware of any well design studies that have been performed to test the drugs efficacy. All I know is that 2 weeks of glucosamine for my 2 year old black lab/border collie has made a huge difference. He used to have 2 or 3 "gimpy" episodes in his right hip every day, they'd last for about 2 minutes. He's had only 1 since I put him of glucosamine and it lasted all of 20 seconds.
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jt512
Mar 9, 2004, 4:42 AM
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In reply to: In reply to: Interesting comments - I am also a veterinary surgeon and I have yet to see any convinving data published about animals (in English). If you have any reference that show that chondroitin sulphate and glucosamine are effective I would be interested. I work in a large referral hospital in the UK and myself and my collegues are not convinced. Much of the evidence for there effectiveness in animals is ancedotal and I am not aware of any well design studies that have been performed to test the drugs efficacy. All I know is that 2 weeks of glucosamine for my 2 year old black lab/border collie has made a huge difference. He used to have 2 or 3 "gimpy" episodes in his right hip every day, they'd last for about 2 minutes. He's had only 1 since I put him of glucosamine and it lasted all of 20 seconds. I think that it has been well established that glucosamine can be effective for arthritis. The question of whether it is helpful for tendon and ligament health is much less clear. -Jay
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cjain
Mar 9, 2004, 11:59 PM
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Very often Glucosamine Sulfate is sold together with Chondroitin Sulfate and that seems to be what most people are buying (including myself, so far). It's become difficult to buy just Glucosamine by itself--I just checked the costco.com web site ( I get mine from Costco) and couldn't find a glucosamine product that didn't have chondroitin added. Also, I understand that Chondroitin is the more expensive part of the mix. But from the absracts I've been reading, I'm getting the impression that high molecular weight Chondroitin is no longer considered very promising and a lot of the current research is focusing on more expensive low molecular weight Chondroitin. The less expensive Glucosamine/Chondroitin mixes don't state what the molecular weight of the Chondroitin is. For example I have the "Kirkland" (Costco store brand) one and it doesn't say anything about molecular weight. So I'd assume they are using less expensive high molecular weight Chondroitin. Makes me wonder whether I'm wasting money and should look around for either just Glucosamine by itself or spring for the more expensive stuff with the high molecular weight Chondroitin. Anyone know more about this?
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jt512
Mar 10, 2004, 12:23 AM
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In reply to: Very often Glucosamine Sulfate is sold together with Chondroitin Sulfate and that seems to be what most people are buying (including myself, so far). It's become difficult to buy just Glucosamine by itself--I just checked the costco.com web site ( I get mine from Costco) and couldn't find a glucosamine product that didn't have chondroitin added. Also, I understand that Chondroitin is the more expensive part of the mix. But from the absracts I've been reading, I'm getting the impression that high molecular weight Chondroitin is no longer considered very promising and a lot of the current research is focusing on more expensive low molecular weight Chondroitin. The less expensive Glucosamine/Chondroitin mixes don't state what the molecular weight of the Chondroitin is. For example I have the "Kirkland" (Costco store brand) one and it doesn't say anything about molecular weight. So I'd assume they are using less expensive high molecular weight Chondroitin. Makes me wonder whether I'm wasting money and should look around for either just Glucosamine by itself or spring for the more expensive stuff with the high molecular weight Chondroitin. Anyone know more about this? I don't know anything about the molecular weight issue, nor much about chondroitin in general. Pure glucosamine sulfate has been shown to be effective for arthritis in numerous clinical trials, so that is what I have always used. It is not difficult to find, though you might have to go to a health food store instead of Costco. -Jay
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pullingpleasure
Mar 10, 2004, 12:26 AM
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if you really want to get your fingers together, take SAMe (S-Adenosylmethionine) 3x a day 200mg per dose along with your 1000mg of glucosamine 3x a day, right and chondroitin 400mg 3x a day. the downside is that it is very expensive.
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jt512
Mar 10, 2004, 1:01 AM
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In reply to: if you really want to get your fingers together, take SAMe (S-Adenosylmethionine) 3x a day 200mg per dose along with your 1000mg of glucosamine 3x a day, right and chondroitin 400mg 3x a day. the downside is that it is very expensive. And probably doesn't do a damn thing for tendons or ligaments. -Jay
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pullingpleasure
Mar 10, 2004, 1:24 PM
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oh, dont think so jt512? PM me and i would be more than happy to send you several references where in scholarly journals it has been shown that supplementation with glucosamin chondroitin and SAMe are extremely beneficial. ..."probably doesnt do a damn thing for tendons or ligaments" probably isnt much proof is it?
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flaredcrack
Mar 10, 2004, 2:09 PM
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I think you have to use high quality products. I used GNC Glucosamin, Chondroitin, MSM products for several years with great results. I tried a different, lower-priced brand, and the benefits seem to be waning. You get what you pay for.
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cclarke
Mar 10, 2004, 2:26 PM
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Pullingpleasure- Could you post the references? I would like to check them out to learn more about SAMe. Thanks. -Chris
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cabdog
Mar 10, 2004, 3:45 PM
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I use puritan pride vitamins. Anybody have good or bad experiences with them? They have great deals. Buy 1 get 2 free!
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cabdog
Mar 10, 2004, 5:03 PM
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anyone?
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mtengaio
Mar 10, 2004, 5:32 PM
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I've been using Puritan's Pride Glucosamine/Condritin combo for about 5 weeks now and I can tell that it is helping my joints and what feels like my tendonitis/bursitis in my inner elbow and my ring finger. I just ordered a new batch of the Glucosamine/Condritin/MSM combo from them as well. I found out about the company through ConsumerLab.com. They tested different brands of Glucosamine and Puritan's Pride was one of the best for its price. So yeah, I've been pleased with the results so far.
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fern
Mar 10, 2004, 7:15 PM
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I read once that there was a possible connection between Chondroitin and elevated cholesterol levels, but I couldn't tease more details out and now I forget even where I read it. Any of you medical types ever heard of this?
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cjain
Mar 10, 2004, 8:28 PM
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From http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/cho_0071.shtml : Some years ago, chondroitin sulfate was investigated for its possible use in atherosclerosis. There was some evidence that it could favorably lower lipid levels and protect against blood clotting. Atheromatous aortic lesions were prevented in animals on high-cholesterol diets. In a clinical trial, 60 patients suffering from coronary artery disease received 2 grams of oral chondroitin sulfate daily for 900 days. During that period, 16 of 60 unsupplemented control patients suffered acute coronary incidents. Only one of the chondroitin sulfate-treated subjects had an acute coronary incident. The same research group later followed up with similarly positive results. More research is needed before any conclusions can be drawn with respect to a possible role for chondroitin sulfate in the treatment or prevention of atherosclerosis. From the same page on the molecular weight issue: Earlier studies using high-molecular-weight chondroitin sulfate, concluded that there was no significant absorption of this high-molecular-weight version of chondroitin sulfate. More recent studies demonstrate that there is probably significant absorption of low-molecular-weight chondroitin sulfate. Absorption appears to occur from the stomach and small intestine. There is also an indication that some chondroitin sulfate, after absorption, does enter the joint space. Studies of the pharmacokinetics of orally administered chondroitin sulfate are ongoing.
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jt512
Mar 10, 2004, 8:31 PM
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In reply to: oh, dont think so jt512? PM me and i would be more than happy to send you several references where in scholarly journals it has been shown that supplementation with glucosamin chondroitin and SAMe are extremely beneficial. I'd be very interested in seeing those references. I'm not sure why I would PM you, though. Either post them or send them to me by PM. -Jay
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pullingpleasure
Mar 11, 2004, 2:38 AM
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sorry about the delay guys...was out climbing, mmm. anyhow heres those references youve all been dying to see: American Journal of Medicine 1987;83:55-59 American Journal of Medicine 1987;83:35-42 Pharmaological aspects of SAMe American Journal of Medicine 1987;83:60-65 SAMe in the treatment of osteoarthritis. Review of the Clinical Studies British Journal of Rheumatology 1997;36:27-31 American Journal of Medicine 1987;83:81-83 Double blind clinical trial of SAMe vs. ibuprofen in the treatment of osteoarthritis American Journal of Medicine 1987;83:72-77 Double blind controlled clinical trial of oral SAMe vs peroxicam in knee osteoarthritis American Journal of Medicine 1987;83:89-94 A long term (2 yrs) clinical trial with SAMe for the treatment of osteoarthritis if you still need more, i might be able to dig up a few more, but i figured this would be sufficient. happy climbing
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jt512
Mar 11, 2004, 3:30 AM
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Pullingpleasure, let's review:
In reply to: if you really want to get your fingers together, take SAMe (S-Adenosylmethionine) 3x a day 200mg per dose along with your 1000mg of glucosamine 3x a day, right and chondroitin 400mg 3x a day...
In reply to: And probably doesn't do a damn thing for tendons or ligaments.
In reply to: oh, dont think so jt512? PM me and i would be more than happy to send you several references where in scholarly journals it has been shown that supplementation with glucosamin chondroitin and SAMe are extremely beneficial.
In reply to: I'd be very interested in seeing those references.
In reply to: anyhow heres those references youve all been dying to see: American Journal of Medicine 1987;83:55-59 American Journal of Medicine 1987;83:35-42 Pharmaological aspects of SAMe American Journal of Medicine 1987;83:60-65 SAMe in the treatment of osteoarthritis. Review of the Clinical Studies British Journal of Rheumatology 1997;36:27-31 American Journal of Medicine 1987;83:81-83 Double blind clinical trial of SAMe vs. ibuprofen in the treatment of osteoarthritis American Journal of Medicine 1987;83:72-77 Double blind controlled clinical trial of oral SAMe vs peroxicam in knee osteoarthritis American Journal of Medicine 1987;83:89-94 A long term (2 yrs) clinical trial with SAMe for the treatment of osteoarthritis if you still need more, i might be able to dig up a few more, but i figured this would be sufficient. Sufficient? They're not even relevant! First of all, we were talking about tendons and ligaments, but judging by the titles, all your references are about treatment of osteoarthritis. Secondly, you said you had references on the combination of SAMe, glucosamine, and chondoitin, but all your references are on SAMe alone. Care to try again? -Jay
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pullingpleasure
Mar 11, 2004, 11:13 AM
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yo jt alright, look-no kidding all of those were for SAMe i have a whole mess of others that deal w/ glucosamine and chrondroitin. Second, in osteoarthritis the dominant clinical findings are that joint deformity, loss of motion and degeneration of cartilage and chondrocytes occurs. i guess you dont know what that means. chondrocytes are the fibers that make up tendons...for the rest of them. i suggest actually reading the articles to see how the other clinical findings effect you
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pullingpleasure
Mar 11, 2004, 11:30 AM
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glucosamine: cartilage is mostly composed of collagen fibrils and feathery strings called proteoglycans. These are replaced continuously in response to use. The limiting chemical in the production of proteoglycans is glucosamine. Together with collagen, glucosamine determines how quickly your joints can repair themselves and recover from the stress of intense weight-bearing stress. your body can make glucosamine from glucose and an amino acid (glutamine). However, glutamine is in constant demand by your immune system muscles and joints. Intense exercise can often overwhelm your glutamine supply (you should also supplement with L-glutamine, but thats not the issue here). you can bypass the joint shortage by taking glucosamine sulfate, which provides glucosamine ready-made for production of proteoglycans. The following study shows that oral glucosamine sulfate can increase proteoglycans by 170%: Pharmatherapeutics 1984;3:538-550. The following 2 studies have proven the effectiveness of glucosamine sulfate supplementation: Current Medical Research & Opinion 1982;8:145-149 Current Topics in Sports Medicine 1984
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pullingpleasure
Mar 11, 2004, 11:50 AM
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Chondroitin: in conjuntion with sulfur, chondroitin forms a big part of the proteoglycans structure of cartilage; it also assists the synovial fluid to lubricate the cartilage. In many cases, the cartilage loses bulk and progressively dries out, becoming stiff and "scratchy." the sliding surfaces become like sandpaper, especially if crystals of uric acid, calcium phosphate or other minerals have gotten into the joint. for a while it was debated whether or not chondroitin could be absorbed due to its high molecular weight of 30,000 (cjain had a blip in his post about this). In contrast glucosamine's molecular weight is 211; it readily passes through the intestinal wall. animal studies in the 80s which used radioactively labeled chond. showed increased levels of radioactivity in the blood, suggesting that the chondroitin molecule somehow got through...however, recent work on human subjects shows negligible absorption of intact chondroitin (Rheumatology International 1992;12:81-88; Journal of Rheumatology 1996;23:1385-1391). nonetheless, studies using oral doses of radioactively labeled chond. continue to show increases in the blood of chondroitin-related and proteoglycan related molecules (Arzneim-Forsh, 1995, Aug;45(8):918-925 Biochemical and pharmacokinetic aspects of oral treatment with chondroitin sulfate). Dr. L Silvestro at Res Pharma in Italy showed that numerous proteoglycans like substances appeared in te blood after oral doses of chondroitin sulfate in healthy men. He showed that some of them had totally lost their sulfur content, indicating that they had been broken down and reconstructed without sulfur in the blood (Semin Thromb Hemos, 1994;20:281-292). other studies show that chondroitin can raise blood levels of hyaluronan, which in your joints is a sticky gel that cements the tissues together. Chondroitin can also increase collagen formation in joints (Glycobiology 1997;7(8):1209-1214; Ther Res 1988;44:845).
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jgrierson
Mar 11, 2004, 1:13 PM
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In reply to: yo jt alright, look-no kidding all of those were for SAMe i have a whole mess of others that deal w/ glucosamine and chrondroitin. Second, in osteoarthritis the dominant clinical findings are that joint deformity, loss of motion and degeneration of cartilage and chondrocytes occurs. i guess you dont know what that means. chondrocytes are the fibers that make up tendons...for the rest of them. i suggest actually reading the articles to see how the other clinical findings effect you Hello Pullingpleasure: :shock: Chondrocytes are actually cells that make up cartilage, i think you'll find that the fibres that make up tendon are actually collagen :D School boy error!! :roll:
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pullingpleasure
Mar 11, 2004, 4:16 PM
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jgrierson youre right, i realized it after i posted the msg. thanks for the correction.
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jt512
Mar 11, 2004, 6:28 PM
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In reply to: jgrierson youre right, i realized it after i posted the msg. thanks for the correction. That little "correction" negates every post you've made in this thread. There is ample evidence of the benefit of glucosamine on joint health, but none, as far as I am aware, on tendon or ligament health. None of the studies you cited have anything to do with effects on tendons and ligaments. -Jay
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pullingpleasure
Mar 12, 2004, 1:46 AM
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you make me laugh
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pullingpleasure
Mar 12, 2004, 1:47 AM
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i quit, do what you will with the info...its no loss to me
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rocknut1
Mar 17, 2004, 5:25 PM
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I have had ACL surgey on both knees and ligaments repaired in both knees. I am going to have a meniscus repaired in April in my left knee. My knees suck, they are both arthritic and I can even tell when its going to rain or snow by how much my knees hurt. My orthopedic doctor says that Glucosamine / Chondroitin is all mental and does nothing. Taking one Alleve a day is better, and it actually does something and costs a 1/4 of the Glucosamine supplements.
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jt512
Mar 17, 2004, 6:58 PM
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In reply to: My orthopedic doctor says that Glucosamine / Chondroitin is all mental and does nothing. If he's talking about arthritis, then what he is saying contradicts a body of placebo-controlled trials. For tendons and ligaments he may be right. -Jay
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cjain
Mar 18, 2004, 10:16 PM
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In reply to: Very often Glucosamine Sulfate is sold together with Chondroitin Sulfate and that seems to be what most people are buying (including myself, so far). It's become difficult to buy just Glucosamine by itself--I just checked the costco.com web site ( I get mine from Costco) and couldn't find a glucosamine product that didn't have chondroitin added. Also, I understand that Chondroitin is the more expensive part of the mix. But from the absracts I've been reading, I'm getting the impression that high molecular weight Chondroitin is no longer considered very promising and a lot of the current research is focusing on more expensive low molecular weight Chondroitin. The less expensive Glucosamine/Chondroitin mixes don't state what the molecular weight of the Chondroitin is. For example I have the "Kirkland" (Costco store brand) one and it doesn't say anything about molecular weight. So I'd assume they are using less expensive high molecular weight Chondroitin. Makes me wonder whether I'm wasting money and should look around for either just Glucosamine by itself or spring for the more expensive stuff with the high molecular weight Chondroitin. Anyone know more about this? By the way, after posting this I emailed Costco customer service asking about the molecular weight of the chondroitin. Turns out that for the Kirkland brand products at least it is high molecular weight: 50,000 daltons. So think I probably have been wasting my money, but then I really don't know much about chondroitin other then just some stuff that I've read. Anyone know more about the molecular weight issue?
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andy_reagan
Mar 19, 2004, 12:46 AM
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The molecular weight issue is a very delicate issue around here. We wish not to talk about it, thereby honoring it in all of its delicateness. Please respect our wishes.
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